Clark (Tom Welling) rushes to find an antidote after Martha (Annette O’Toole) is infected with a toxic virus and falls into a coma, but when Clark also falls ill, it is up to Jonathan to find a cure in time. To further complicate things, Dr. Bryce (guest star Emmanuelle Vaugier) demands an explanation from Jonathan when he refuses to let her treat Clark.
Kristin Kreuk, Michael Rosenbaum, Allison Mack, Sam Jones III and John Glover also star. Bill Gereghty directed the episode written by Matthew Okumura.
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